Stephen Bradley's side travel to North Macedonia with a 3-1 aggregate lead after last week's first leg victory at Tallaght Stadium. Here's all the information you need to know ahead of the game, including how to watch Shamrock Rovers v Shkupi.
When is Shamrock Rovers v Shkupi?
Kick off is at 8pm on Tuesday the 9th of August.
How to watch Shamrock Rovers v Shkupi
The game is available on LOI TV for €10.
South African broadcaster Super Sport 2 are believed to be showing the match, though they are not on any TV provider in this country.
A wonderful strike from Gary O'Neill deep into injury time sealed Shamrock Rovers' 3-1 first leg win last weekend. Graham Burke and Dylan Watts gave the Hoops a 2-0 lead in the first half, before the North Macedonian side pulled one back with a quarter of an hour remaining.
Rovers beat Maltese outfit Hibernians in the first qualifying round before losing 4-2 on aggregate against Ludogorets.
Shamrock Rovers are sitting six points clear at the summit of the League of Ireland Premier Division, but they do have a game in hand over nearest competitors Dundalk.
Rory Gaffney has been in terrific form this season and with the return of Graham Burke to full fitness, goals should not be a problem.
Chris McCann and Dylan Watts have also been in fine form on the creative front while defender Dan Cleary has made a great impact since signing from St. Johnstone a couple of weeks ago.
Once Shamrock Rovers don't lose by two or more goals, it will guarantee them a place in the Europa League playoff round. They will play the losers of Qarabeg and Basel in the next round.
It's been a great European campaign by the reigning League of Ireland Premier Division champions who will feel that an autumn of European football is within their grasp.