It really doesn't seem like it's going to be their year. After an inauspicious start to the season, Liverpool have been dealt another unfortunate blow.
Having previously missed three games through suspension, Sadio Mane is set to face another 'spell on the sidelines' according to Liverpool's official club website.
Playing for Senegal in a World Cup qualifier against the Cape Verde Islands on Saturday, Mane sustained a hamstring injury.
Substituted off after 89 minutes with Senegal leading 2-0, Mane is now set to be unavailable to Jurgen Klopp for the next 6 weeks.
Sadio Mane is facing a spell on the sidelines after sustaining a hamstring injury on international duty, Liverpool FC can confirm.
The winger was substituted 89 minutes into Senegal's 2-0 World Cup qualifying win over the Cape Verde Islands on Saturday.
And it has now been confirmed that he picked up an injury during that fixture that could keep him out of action for up to six weeks.
One of the outstanding threats in a Liverpool side increasingly dependent upon it's attacking prowess, the loss of Mane has arrived at a highly inconvenient time for Klopp.
Hosting Manchester United on Saturday, the next six weeks will also see Liverpool face off against Spurs and Chelsea.
Perhaps most crucial of all however will be the expected absence of Mane when Liverpool travel to face Sevilla later next month.
After two opening draws, this tie may well determine Liverpool's Champions League fate for this season. Needless to say, Liverpool fans have by and large taken this news about as well as one would expect.
Sadio Mane out for six weeks with hamstring injury.
— Sachin Nakrani (@SachinNakrani) October 10, 2017
LFC fans in the summer: "brilliant, we won't lose players mid season to the AFCON.
Football Gods: "LOL, that's cute." *Injure Mane*
— John O'Sullivan (@NotoriousJOS) October 10, 2017
With Senegal yet to confirm their place in next year's World Cup, this news will bring no joy to them ahead of their crucial qualifier against South Africa early next month.
Having been confirmed on the 2017 Ballon D'or shortlist yesterday, Liverpool fans will be hopeful that Mane's lost will be the last of their worries for this international window.
With Coutinho expected to play his part as Brazil see out their qualifying campaign this evening against Chile, losing the Brazilian would be disastrous ahead of United's visit on Saturday.