After such a fine start to the 2018/19 season, Luke Shaw has been hit with a fresh injury. Caught in a completely innocuous collision with Spain's Dani Carvajal, Shaw looked to be in some distress as he was forced from the pitch prematurely.
Having started his first game back in the English team superbly, the Manchester United full-back played an exquisite pass into his club-mate Marcus Rashford for England's opener.
Marauding up and down the left-flank, Shaw looked to be delivering upon the initial promise that had suffered so many set-backs in his admittedly short career.
With the second-half only a few minutes old, and England now trailing by two goals to one, Shaw appeared to catch his head on Carvajal's leg.
Although the Real Madrid full-back clearly had no idea of the magnitude of what had occurred, the United full-back was clearly distressed.
Given a rigorous check-up on the pitch from England's medical team, it was adjudged that Shaw would have to be taken off; Tottenham Hotspur's Danny Rose coming in to replace him.
With many fearing the worst for Luke Shaw, it was reported shortly afterward that he was doing well, and had been contacting his family from within the England dressing-room to inform them of his condition.
Here's hoping that there will not be another set-back for the promising full-back.
You can watch the video of the Luke Shaw injury below - but it does make for difficult viewing.